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Chapter 39 of 78
黄帝内经·素问
The Yellow Emperor asked: I have heard that one who is skilled in discussing the Way of Heaven can certainly apply the Way of Heaven to human affairs; one who is skilled in discussing antiquity can certainly integrate the experiences of antiquity with the present; one who is skilled in discussing others can certainly verify through comparison with oneself. In this way, principles will not be confused, and essential points can be fully grasped—this is called "understanding." Now I wish to ask you, Sir, whether you can enable me to understand illness through inquiry, to see signs through observation, to palpate the site of disease through touch, and to verify these on my own body, thereby enlightening ignorance and dispelling doubt?
Qi Bo bowed twice and touched his head to the ground before answering: What aspect of principles does Your Majesty wish to ask about?
The Yellow Emperor said: I wish to know—when a person's five viscera suddenly develop pain, what qi causes it?
Qi Bo answered: The qi and blood in the channels and vessels flow without ceasing, circulating through the entire body without stopping. When cold pathogen invades the channels and vessels, it causes qi and blood to stagnate and slow, becoming rough and impeded so that they cannot flow freely. If cold pathogen lodges outside the channels and vessels, then the blood outside the channels diminishes; if it lodges within the channels, then qi is obstructed—therefore sudden pain arises.
The Yellow Emperor asked: Among these pains, some stop suddenly, some are severe and unrelenting, some are so painful that they cannot bear pressure, some stop after pressure is applied, some show no effect from pressure, some have a throbbing sensation under the hand when pressed, some involve the heart and back pulling toward each other in pain, some involve the flanks and lower abdomen pulling toward each other in pain, some involve abdominal pain radiating to the inner thighs, some over time form accumulations, some involve sudden excruciating pain with loss of consciousness followed by revival after a while, some involve pain with vomiting, some involve pain followed by diarrhea, some involve pain with constipation and obstruction. These pains all manifest differently—how should they be distinguished?
Qi Bo said:
The Yellow Emperor said: These are things that can be known through inquiry. What then can be seen through observation?
Qi Bo said: The five viscera and six bowels each have corresponding regions on the face. Observe the changes in the five colors: yellow and red indicate heat, white indicates cold, and blue-black indicates pain—these are what can be seen through observation.
The Yellow Emperor said: What can be detected through palpation?
Qi Bo said: Examining the pulse of the dominant disease, if the pulse is hard, if blood is replete and full, or if it is sunken and depressed, all of these can be known through palpation.
The Yellow Emperor said: Excellent. I understand that many diseases arise from disharmony of qi movement. Anger causes qi to rise, joy causes qi to relax, grief causes qi to dissipate, fear causes qi to descend, cold causes qi to contract, heat causes qi to leak, fright causes qi to become chaotic, overexertion causes qi to be depleted, and pensiveness causes qi to bind. These nine changes in qi movement are different—what diseases do they give rise to?
Qi Bo said:
The core academic ideas of this chapter can be summarized in three points:
The early model of "pain due to blockage" and "pain due to malnourishment"
With cold pathogen as the main thread, the chapter repeatedly explains that pain arises primarily from two sources: first, roughness and stagnation of qi and blood with blockage of the channels and vessels—that is, "pain due to blockage"; second, blood deficiency with failure to nourish the channels and vessels—as in "when the pulse is impeded, blood becomes deficient; when blood is deficient, pain arises"—the prototype of the later concept "pain due to malnourishment." Cold is characterized by contraction and congealing, so it most readily produces this pathological state.
The combined three methods of diagnosis for pain syndromes
The Yellow Emperor explicitly proposes "knowable through speech, visible through observation, obtainable through palpation"—that is, the integration of inquiry, observation, and palpation. The chapter not only asks in detail about the nature, location, and accompanying symptoms of pain, but also discusses the five-color observation and pulse palpation, reflecting the relatively systematic diagnostic approach already formed during the era of the Inner Canon.
The "nine qi" pathogenesis of "hundred diseases arising from qi"
The latter half of the chapter categorizes nine factors—anger, joy, grief, fear, cold, heat, fright, overexertion, and pensiveness—into nine abnormal changes of qi movement: rising, relaxing, dissipating, descending, contracting, leaking, becoming chaotic, becoming depleted, and binding. This shows that the ancients already recognized that emotions, external environment, and physical exertion may all cause disease by affecting the qi movement of the entire body, not only through physical injury.
"Pain due to blockage" and "pain due to malnourishment"
From the perspective of modern medicine, the mechanisms by which cold pathogen causes pain are partially connected to cold stimulation leading to vasoconstriction, smooth muscle spasm, local tissue ischemia and hypoxia, and inflammatory factors irritating nerve endings. The ancients used descriptions such as "cold qi lodging outside the channels" and "channels contracting and curling upon cold," which, while lacking microscopic evidence, captured the pathological chain of "cold—contraction—qi and blood failing to move—pain."
The differential significance of pain characteristics
Descriptions in the chapter such as "pressure stops the pain," "pressure is of no benefit," and "severe pain that cannot be pressed" share similar logic with modern clinical physical examination findings concerning tenderness, rebound tenderness, and muscle guarding. For example, severe abdominal pain with guarding often suggests inflammatory or organic lesions, while pain relieved by pressure is more commonly related to deficiency-cold or spasm. However, the ancients could only explain these from the level of qi, blood, cold, and heat, lacking the foundation of modern anatomy and pathology.
The phenomenon of referred pain
"Heart and back pulling toward each other in pain" and "flanks and lower abdomen pulling toward each other in pain" resemble referred pain in modern medicine. The ancients explained such phenomena through channel theory, which has some basis in empirical observation, but channel theory still cannot be fully mapped to modern anatomy.
Emotional pathogenesis and the nine qi
"Anger causes qi to rise," "fear causes qi to descend," "pensiveness causes qi to bind"—these have points of corroboration with modern psychoneuroimmunology and stress response research. Emotions do affect the autonomic nervous system, endocrine function, and digestive function; for example, chronic anxiety can lead to gastrointestinal dysfunction, and outbursts of anger can induce elevated blood pressure. However, the ancients directly attributed emotional changes to the ascending and descending, exiting and entering of "qi"—a theoretical model that cannot be simplistically equated with modern physiology.
Historical limitations
The five-color diagnosis, pulse diagnosis, and other content in this chapter belong to traditional diagnostic methods with some empirical basis, but they lack strict evidence-based foundations, and their sensitivity and specificity are limited—they cannot serve independently as modern diagnostic standards. For descriptions such as "pain so severe that one loses consciousness, with revival upon qi returning," which may encompass conditions such as syncope and shock, the ancients could only explain matters in terms of qi due to their conditions—modern emergency measures should be employed in practice.
Associated Concepts
Cold causes contraction · Pain due to blockage · Pain due to malnourishment · Nine qi pathogenesis · Nutritive and defensive qi · Five viscera and six bowels color diagnostic mapping · The Chong Vessel of the extraordinary vessels · Foot Jueyin Liver Channel · Upper, middle, and lower burners · Sunsun (undigested food diarrhea)
Further Reading
Plain Questions · Discourse on Regulating the Channels — on deficiency-excess pathogenesis and the relationship between qi and blood
Plain Questions · Discourse on Ultimate Truth and Great Essentiality — the nineteen items on pathogenesis
Miraculous Pivot · Original Spirit — correspondence between emotions and the five viscera
Miraculous Pivot · Channels and Vessels — channel pathways and their disorders
Complete Works of Jingyue · Miscellaneous Syndromes · Heart and Abdominal Pain — later development of theory and methods for pain syndromes
— Compiled by Buguā
This content is based on classical Chinese medicine texts and is provided solely for traditional cultural study and research. It does not constitute any medical diagnosis, medication, or treatment advice. If you feel unwell, please seek medical attention promptly.